The Fast Facts

  • Although aging is an inevitable part of life, many of us want to retain our youthfulness for as long as possible.
  • While healthy habits are the best way to support healthy aging, certain supplements —like curcumin, collagen, vitamin C, and vitamin E—may help slow the effects of aging.
  • Top anti-aging supplements include Thorne Curcumin Phytosome Capsules and Mindbodygreen Beauty & Gut Collagen+.
Thorne, Mindbodygreen, Nutricost, and Double Wood anti-aging supplements.Share on Pinterest
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You can’t stop aging, but you can make dietary and lifestyle changes to slow certain aging processes and reduce your risk of age-related diseases. That’s why you’ll see this article mostly use terms like “support healthy aging” rather than “anti-aging.”

The main causes of aging include accumulated cellular damage caused by reactive molecules called free radicals and the shortening of telomeres, which are structures at the ends of chromosomes that play an important role in cellular division.

Following a nutrient-dense diet, exercising regularly, and avoiding smoking and excessive alcohol intake are the best ways to support healthy aging and slow the effects of aging on your body. That said, scientists have identified numerous compounds that may slow certain aging processes and help decrease the risk of age-related disease.

Here are our picks of the best healthy aging supplements in 2026.

Product
Best
Healthy aging benefits
Form
Price
curcumin supplement
• may slow cellular aging
• promotes longevity
• protects against age-related damage
capsule
$36 
EGCG supplement
• may support longevity
• protects against age-related diseases
• may support heart health
• possible skin-aging benefits
tea
$15.25
collagen supplement
• supports skin elasticity & structure
• may reduce wrinkles and signs of aging
powder
$70
CoQ10 supplement
• replenishes declining CoQ10 levels
• supports energy production
• protects against cellular damage
capsule
$13.95
vitamin C supplement
• protects cells from aging damage
• supports immune health
& regulates inflammation
• may boost overall healthy aging
capsule
$23
vitamin E supplement
• decreases free radicals & oxidative stress
• supports immune function & regulates inflammation
• may support age-related conditions
softgel
$18.95
L-theanine supplement
• may help slow skin aging
• helps reduce inflammation & cell damage
• may promote longevity
• potential brain health support
capsule
$19.95
NMN supplement
• supports NAD+ levels (which decline with age)
• may support healthy aging processes
• potential healthy aging effects
capsule
$48.95

To help you decide which products are worth considering, Healthline researched the best healthy aging supplements using the following criteria:

  • Vetting: We have vetted all the products included to ensure that they meet Healthline’s medical and business standards. These products meet the Food and Drug Administration (FDA) allowable health claims and labeling requirements, and the manufacturer produces them in facilities that follow current good manufacturing practices (CGMPs).
  • Ingredients: We aimed to include several options that are free of potentially unwanted ingredients, such as artificial flavors or sweeteners, certain allergens, and additives and preservatives.
  • Price: We included supplements to fit a wide range of budgets.
  • User reviews: All the vitamins on this list have mostly favorable customer reviews.
  • Trustworthiness: We also chose products only from medically credible companies that follow industry best standards. Many also provide objective measures of trust, like third-party certifications.

The following supplements may also support healthy aging.

  • Rhodiola: This medicinal plant has potent anti-inflammatory properties, with a laboratory study suggesting it may help promote longevity.
  • Astragalus: This herb is used in traditional Chinese medicine to reduce stress. It may help combat aging by reducing oxidative stress, promoting immune function, and preventing cellular damage.
  • Fisetin: This is a flavonoid compound that’s considered a senotherapeutic, meaning it may kill senescent cells.
  • Resveratrol: This polyphenol antioxidant, found in grapes, berries, peanuts, and red wine, may promote longevity by activating certain enzymes called sirtuins. Animal studies indicate that resveratrol may support healthy aging, but human research is needed.
  • Sulforaphane: This is a sulfur compound concentrated in cruciferous vegetables like broccoli that’s known to have powerful anti-inflammatory properties. According to research on mice, it may help slow skin aging by boosting the body’s natural defenses against damage and inflammation.
  • Crocin: This is a yellow carotenoid pigment found in the spice saffron. Human and animal studies have shown that crocin offers many health benefits, including anti-inflammatory, antioxidant, and anti-anxiety and antidepressant effects.
Medical Perspective

“Slowing cellular aging is about preserving your health from within, while improving the outward signs is only skin deep. True longevity means nurturing your body at the cellular level rather than masking age at the surface.”

Jillian Kubala, MS, RD

Learn more about habits to form now for a longer life.

Quotes represent the opinions of our medical experts. All content is strictly informational and should not be considered medical advice.

Shopping guide

Before adding a new supplement to your routine, talk with a doctor — especially if you have an underlying health condition or are taking medication.

As supplements are regulated differently than medications in the United States and many other countries, always look for third-party certification on the label to ensure you’re getting a high quality product.

Check out these articles to help make shopping for healthy aging supplements a breeze:

Studies show that several supplements may help support healthy aging, such as CoQ10, vitamins C and E, and curcumin.

However, supplements are not a replacement for healthy habits. Eating a healthy diet and continuing to exercise will help reduce the risk of some age-related conditions.

Most studies on supplements have been conducted on animals. More research is needed to determine how effective they are at encouraging healthy aging in humans.

However, research is promising. All of the supplements in this article have age-protective properties, including antioxidant effects and reductions in inflammatory markers associated with aging.

No, supplements cannot slow down aging. However, they can help support your body as it ages and may help reduce the risk of developing age-related conditions alongside a healthy diet and exercise.

In addition to following a healthy diet and lifestyle, taking certain supplements may help slow the aging process and promote a long, healthy life.

Nevertheless, the best way to promote longevity and overall health is to take care of your body by eating nutritious foods, exercising regularly, and reducing stress.